Phage Publication, Perfect!

Our latest paper is out in mBio today! If you've induced phages, you may have wondered if you can do the 'opposite' - block entry into lysogeny. You can, using protein synthesis inhibitors! Better still, this yields a potent synergy, functionally turning a temperate phage into a virulent one. This was a lot of work, spanning two parental leaves (not both for the same person), and a big group effort to push it over the finish line - but it came together beautifully.

Check it out here: Temperate phage-antibiotic synergy across antibiotic classes reveals new mechanism for preventing lysogeny | mBio (asm.org)

Alexander Hynes